GDF15, His, Human：Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and o

產品型號：Z05341

更新時間：2025-11-06

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產品介紹

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.

產品簡介

Species

Human

Protein Construction

His	GDF15 (Ala197-Ile308) Accession # Q99988-1
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.

Expression System

E.coli

Theoretical Molecular Weight

13.5 kDa

Apparent Molecular Weight

The protein migrates to 15-16 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in 50mM HAc (pH 2.9).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9).

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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